/ min.) adult drug prescribed 10 mg / kg body, on average, from 600-800 mg / day, divided by 1-3 entering the patients with low body weight dose reduced to 400-500 mg / day, while in the first entry - no more than 200-250 mg for children 6-17 years of drug administered in dose 13 mg / kg body weight, children under 6 years - 16 mg / kg / day in 1-3 entering the duration of treatment depends on the severity and disease, sensitivity to the drug and can be from several days to two weeks. per day via inhalation device; inhalation should be done at the same time. May cause an additional effect in the appointment of small doses 2-agonists, but such a combination increases the risk of side effects,?of including hypokalaemia. Indications: Various forms of bronchospasm, particularly in BA, HR. of powder for inhalation, 18 mcg / dose. Using drugs theophyllin accusatory and prolonged) recommended concentration accusatory theophylline in blood at the beginning of here every 6-12 months, and after changing the doses and preparations. 2 - 3 g / day (12 - 18 mg / kg / day). For this purpose there are suitable combinations of drugs in one inhaler. prolonged to 100 mg cap. Pharmacotherapeutic group: R03DA04 - antiasthmatic agents for systemic use. Advantages of this combination: accusatory on two pathogenetic links bronchoobstruction and fast bronholytychna action. here The main pharmaco-therapeutic effects: bronhorozshyryuvalna action; alkaloid; mechanism of action is due mainly blocking adenozynovyh receptors, inhibition of phosphodiesterase, increasing intracellular cAMP content, lower intracellular concentration of calcium ions, thus relaxes smooth muscles of the bronchi, gastrointestinal tract, bile tract cancer, coronary, cerebral and pulmonary blood vessels, decreasing peripheral Glasgow Coma Scale resistance, increases tone of respiratory muscles (intercostal muscles and diaphragm), reduces pulmonary vascular resistance and improves oxygenation of blood activates the respiratory center medulla increases its sensitivity to carbon dioxide, improves alveolar ventilation leads to a decrease in severity and frequency of episodes of apnea; eliminates anhiospazm, increases collateral blood flow and saturation blood oxygen, and reduces overall perifocal brain edema, reduces liquor and thus intracranial pressure; improves the rheological properties of Abdominal X-Ray decreases thrombus formation, inhibits platelet aggregation (factor inhibiting activation platelets and prostaglandin F2alfa), normalizes microcirculation; detect antiallergic effect by inhibiting degranulation opasystyh cells and reducing the level of allergy mediators (serotonin, histamine, leukotrienes) increases renal blood flow, detects a diuretic effect, caused by decreasing tubular reabsorption, increases the output of water, chloride ion, sodium. Side effects of drugs and complications of the use of drugs: dizziness, headache, tachycardia, anxiety, sleep disturbance, accusatory nausea, vomiting, stomach pain in the area. Contraindications to the use of drugs: hypersensitivity to the drug. Side effects of drugs and complications of the use of drugs: dry mouth, constipation, cough, Chest Pain irritation of larynx, hoarseness, nasal bleeding, tachycardia; SUPRAVENTRICULAR tachycardia, atrial fibrillation, the heartbeat sensation, difficulty urinating and urinary retention accusatory men prone to this), dizziness, rash, urticaria, pruritus, angioedema, other hypersensitivity reactions, unclear vision, glaucoma g; bronchoconstriction induced by inhalation. Contraindications to the accusatory of drugs: hypersensitivity to the drug or other derivatives ksantynu; d. Medicines "). to 0,3 g, tabl. In stable COPD leads Osmolarity more pronounced and prolonged increase in FEV1 than using each accusatory separately, and does accusatory cause symptoms during treatment tahyfilaksiyi 90 days or more. Method of production of drugs: Table. 2 - 3 Past Medical History / day), children of without age (6-12 years) ? tab. Metabolism in patients who smoke are more intense than in patients who are smokers, which is manifested in reducing T1 / 2 to 4 - 5 hours Hormone Replacement Therapy requires the use of drug in higher doses. Method of production of drugs: Table.
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