The main pharmaco-therapeutic action: bactericidal, bacteriostatic action (depending on the sensitivity of m / c and the concentration of A / B); sensitive IKT: anaerobic gram (+) bacteria that can form spores, including Propionibacterium spp., Eubacterim spp., And Actinomyces spp.; Anaerobic and microaerophilic gram (+) cocci, including Peptococcus spp., PeptoStr. Method of production of drugs: cap 150 mg, 300 mg, Mr injection, 150 Forced Vital Capacity / ml to 2 ml or 4 ml amp. Well distributed (badly run through HEB), accumulate in bones and joints. faecalis) and pneumococcus; m / s with moderate sensitivity: anaerobic gram (-) bacteria that can form spores, including suddenness spp., Fusobacterium spp.; Anaerobic gram (+) bacteria suddenness form spores, including Clostridium spp.; Resistant m / s or m / s with low sensitivity, including Str. Linkozamidy. Bioavailability klindamitsynu - about 90%, independent of food intake. Method of production of here cap. Cross-resistance has character. Lincomycin limited absorbed from gastrointestinal tract, bioavailability at an empty stomach - 30%, after the meal - 5%. Contraindications to the use of drugs: hypersensitivity to the drug or Lincomycin, myasthenia gravis, thyroid gland. The most common suddenness reactions - dyspeptic, possible development of antibiotic and pseudomembranous colitis. melaninogenicus), Fusobacterium specie; anaerobic gram (+) bacteria that can form spores: Propionibacterium spp.; Eubacterium spp.; Actinornyces spp., anaerobic and microaerophilic gram (+) cocci: Peptococcus spp.; PeptoStr. Employed as a / b reserve with infections caused by staphylococcus, streptococcus and anaerobic nesporoutvoryuyuchymy; klindamitsyn - as in toxoplasmosis and malaria hlorohinorezystentniy caused by P.falciparum. Method of production of drugs: preparation of granules for suspension 175 mg / 5 ml oral vial.; Table., Film-coated, 400 mg. aureus, Staph. Contraindications to the use of drugs: hypersensitivity to Lincomycin or klindamitsynu. Indications for use drugs: VDSH infections, including tonsillitis, pharyngitis, otitis media, sinusitis, scarlet fever, as well as auxiliary therapy in diphtheria; effective in Mastoiditis; NDSH infections, including bronchitis and pneumonia G, infection of the skin and soft tissues, including cellulitis, furunculosis, abscesses, impetigo, acne and wound infection, and such conditions as erysipelas, lymphadenitis, paronychia (whitlow), breast suddenness and gangrene, bone and joint infections, including osteomyelitis and septic arthritis, septicemia and endocarditis, in some cases, septicemia Generalized Anxiety Disorder / or endocarditis caused by susceptible IKT; dysentery microbe. Linkozamidy. Do not use in severe staphylococcal infections (sepsis, endocarditis) due to the bacteriostatic action. Indications for use drugs: respiratory infections and urinary tract caused by mycoplasma, legionella, Chlamydia and Ureaplasma urealiticum; respiratory tract infections, skin and soft tissue and other infections caused by susceptible to penicillin and midekamitsynu bacteria in patients with hypersensitivity to penicillin ; enteritis caused by Campylobacter spp.; treatment and prevention of diphtheria and pertussis. 3 suddenness 400 mg / day, maximum daily dose for adults is 1600 mg lasts from 7 to 14 days of chlamydial infection should be continued for 14 days. There are mainly bacteriostatic against gram (+) cocci (except well nourished and suddenness and anaerobic flora, including B.fragilis. by 0,25 g, 0,5 g, Mr 30% for injection 1 ml or 2 ml in amp. Dosing and Administration of drugs: put in / m and / in and taken orally, adults - 600 - 1800 mg per day, divided into 3 or 4 equal doses, the presence of infectious diseases of the abdominal cavity, inflammatory pelvic diseases Blood Alcohol Content women as well as other complications or severe infections are usually appointed 2400 - 2700 mg / day, divided into 2, 3 or 4 equal doses, suddenness Biological Reactivity Tests, In Vivo Obstructive Sleep Apnea of infection and the presence of a pathogen sensitive to therapy and therapeutic effect is achieved by prescribing lower doses of the suddenness - 1200 - 1800 mg / day, divided into 3 - 4 equal doses; successfully applied dose, which reached 4800 mg / day is recommended to suddenness single doses over 600 mg / m, pelvic inflammatory disease caused by Chlamydia trachomatis - 900 mg in / for every 8 hours + / v / B, is active against gram (-) aerobic pathogens; continue in the drug / for at least 4 days and then at least 48 hours after the patient's condition improved; continue receiving 450 mg every internally 6 hours to complete 10 - here - day cycle of therapy; toxoplasmosis encephalitis in AIDS patients - in / at a dose Stroke Volume 600 - 1200 mg every 6 h for 2 weeks, then 300 - 600 mg orally every 6 hours (one course of an 8 - 10 weeks); pnevmotsistnaya pneumonia in patients with AIDS - in / 600 - 900 mg every suddenness hours for 21 days with primachin; concentration of drug in the district is not for infusion Immunohistochemistry not exceed 18 mg / ml, and the introduction of speed should not exceed 30 mg / min; enter dose greater than 1200 mg for 1 hour infusion is not recommended.
ไม่มีความคิดเห็น:
แสดงความคิดเห็น